(2007) Sunshine

as Cassie

(2004) Troy

as Briseis

(2007) 28 Weeks Later

as Scarlet

(2006) Marie Antoinette

as Duchesse de Polignac

(2002) Star Wars: Episode II - Attack of the Clones

as Dormé

(1994) Dallas Doll

as Rastus Sommers

(2004) Wicker Park

as Alex

(2009) Adam

as Beth Buchwald

(2002) City of Ghosts

as Sabrina

(2021) Shark

as Sofie

(2006) The Tenants

as Irene Bell

(2010) Get Him to the Greek

as Jackie Q

(2023) Teenage Mutant Ninja Turtles: Mutant Mayhem

as Leatherhead (voice)

(1999) Two Hands

as Alex

(2006) The Dead Girl

as Leah

(2009) Knowing

as Diana Wayland

(2021) Puff: Wonders of the Reef

as Narrator (voice)

(2003) The Rage in Placid Lake

as Gemma Taylor

(2007) Just Buried

as Roberta Knickle

(2003) Take Away

as Sonja Stilano

(2008) The Tender Hook

as Iris

(2000) The Goddess of 1967

as B.G.

(2003) I Capture the Castle

as Rose Mortmain

(2011) Insidious

as Renai Lambert

(2011) X-Men: First Class

as Moira MacTaggert

(2013) The Turning

as Rae

(2013) Insidious: Chapter 2

as Renai Lambert

(2011) Bridesmaids

as Helen Harris

(2013) The Place Beyond the Pines

as Jennifer Cross

(2013) I Give It a Year

as Nat

(2013) The Internship

as Dana Simms

(2007) Code Red: The Making of '28 Weeks Later'

as Self / Scarlet

(2000) My Mother Frank

as Jenny

(2014) Neighbors

as Kelly Radner

(2015) Spy

as Raina Boyanov

(2014) This Is Where I Leave You

as Penny Moore

(2014) Annie

as Grace Farell

(2023) Insidious: The Red Door

as Renai Lambert

(2014) Adult Beginners

as Justine

(2022) G'day

as Ruby (voice)

(2016) X-Men: Apocalypse

as Moira MacTaggert

(2024) Ezra

as Jenna

(2016) Neighbors 2: Sorority Rising

as Kelly Radner

Tow

as Amanda Ogle

(2016) The Meddler

as Lori Minervini

(2022) Spirited

as Ms. Blansky

(2025) If I Had Legs I’d Kick You

as Linda

(2003) The Night We Called It a Day

as Audrey Appleby

(2015) Unity

as Narrator (voice)

(2024) Tree's Blood

as Zamora

(2010) I Love You Too

as Verity

(2018) Peter Rabbit

as Beatrix 'Bea' Potter / Jemima Puddle-Duck (voice)

(2011) Children of the Atom - Filming X-Men: First Class

as ---

(2017) The Immortal Life of Henrietta Lacks

as Rebecca Skloot

(2018) Juliet, Naked

as Annie Platt

(2017) I Love You, Daddy

as Grace Cullen

(2018) Instant Family

as Ellie Wagner

(2018) Insidious: The Last Key

as Renai Lambert

(2020) Like a Boss

as Mel Paige

(2019) I Am Mother

as Mother (voice)

(2021) Peter Rabbit 2: The Runaway

as Bea

(2020) Irresistible

as Faith Brewster

(2010) Gaze

as Self (archive footage)

(2019) Jexi

as Jexi (voice)

(2017) Martha the Monster

as Martha

(1999) The Date

as Sophie

(2001) The Pitch

as Girl

(2022) Seriously Red

as Elvis

(1997) Murder Call

as ---

(2021) Physical

as Sheila Rubin

(1999) Rove

as Self

(1993) Late Night with Conan O'Brien

as ---

(2007) Damages

as Ellen Parsons

(2005) Casanova

as Edith

(1995) Echo Point

as Belinda O'Connor

(1997) Big Sky

as Angie

(2009) The Justin Lee Collins Show

as Self - Guest

(2014) Late Night with Seth Meyers

as Self

(2011) Portlandia

as Fred's Girlfriend

(2004) Project Runway

as Self - Guest Judge

(2019) The Kelly Clarkson Show

as ---

(2019) The Boys

as Rose Byrne (uncredited)

(2018) Bluey

as Brandy (voice)

(2016) Angie Tribeca

as Norrah Newt

(2014) The Tonight Show Starring Jimmy Fallon

as ---

(2009) Watch What Happens Live with Andy Cohen

as Self - Guest

(2014) Last Week Tonight with John Oliver

as Boeing Executive

(2020) Mrs. America

as Gloria Steinem

(2014) The Tonight Show Starring Jimmy Fallon

as Self

(2014) The Tonight Show Starring Jimmy Fallon

as Self - Guest

(2005) American Dad!

as Jenny (voice)

(2013) Hollywood Game Night

as Self

(2014) Off Camera with Sam Jones

as Self

(2009) Late Night with Jimmy Fallon

as Self

(2023) Platonic

as Sylvia

(2015) Close Up with The Hollywood Reporter

as Self

The Good Daughter

as Samantha Quinn