(1993) True Romance

as Alabama Whitman

(2001) Human Nature

as Lila Jute

(1994) Ed Wood

as Kathy O'Hara

(1998) The Hi-Lo Country

as Mona

(1996) Infinity

as Arline Greenbaum

(1996) Flirting with Disaster

as Nancy Coplin

(2002) The Badge

as Scarlett

(1997) Lost Highway

as Renee Madison / Alice Wakefield

(1997) Nightwatch

as Katherine

(1994) Holy Matrimony

as Havana

(1987) A Nightmare on Elm Street 3: Dream Warriors

as Kristen Parker

(1995) Beyond Rangoon

as Laura Bowman

(1999) Stigmata

as Frankie Paige

(1991) Wildflower

as Alice Guthrie

(1999) Bringing Out the Dead

as Mary Burke

(2006) Fast Food Nation

as Cindy

(2003) Holes

as Katherine "Kissin' Kate" Barlow

(2002) Tiptoes

as Lucy

(1991) The Indian Runner

as Dorothy

(2000) Little Nicky

as Valerie Veran

(1997) Pretty as a Picture: The Art of David Lynch

as Self

(1993) Ethan Frome

as Mattie Silver

(1991) Prayer of the Rollerboys

as Casey

(1996) The Secret Agent

as Winnie

(2007) Certifiably Jonathan

as Self

(1999) Goodbye Lover

as Sandra Dunmore

(2012) Girl in Progress

as Ms. Armstrong

(1993) Trouble Bound

as Kit Califano

(2014) Boyhood

as Mom

(1988) Far North

as Jilly

(2002) Searching for Debra Winger

as Self

(2013) A Glimpse Inside the Mind of Charles Swan III

as Izzy

(1987) Pretty Smart

as Zero

(1987) Daddy

as Stacy

(2007) The Manufacturing of 'Fast Food Nation'

as Self

(1992) Inside Monkey Zetterland

as Grace

(2013) Vijay and I

as Julia

(2016) Richard Linklater: Dream Is Destiny

as Self

(1991) Dillinger

as Polly Hamilton

(1989) Uncle Buck

as Additional Voices (voice)

(2014) Electric Slide

as Tina

(2023) Gonzo Girl

as Claudia

(1990) Made in Hollywood

as Tammy

(2015) The Wannabe

as Rose

(2014) 9 Kisses

as Woman in Park

(1988) Time Out

as Lucy

The Last Disturbance of Madeline Hynde

as ---

They Will Kill You

as ---

(2017) Permanent

as Jeanne Dixon

(2018) Survivor's Guide to Prison

as Self

(1994) Betrayed by Love

as Deanna

(2003) Abby Singer

as Patricia Arquette (uncredited)

(2008) A Single Woman

as Storyteller

(2019) Otherhood

as Gillian Lieberman

(2019) Toy Story 4

as Harmony’s Mom (voice)

(2014) The Wait

as Psychic

(2020) You Cannot Kill David Arquette

as Self

(2004) Ed Wood: Pie Plates Over Hollywood

as Self (archive footage)

(1989) The Edge

as Raped Woman

(2020) Kiss the Ground

as Self - Actor / Founder, GiveLove.org

(2015) Twelve Years

as Self

(2010) Never Sleep Again: The Elm Street Legacy

as Self (archive footage)

(2021) Quentin Tarantino: From a Movie Buff to a Hollywood Legend

as Self (archive footage)

(2022) Severance

as Harmony Cobel / Mrs. Selvig

(2005) Medium

as Allison Dubois

(2003) The Ellen DeGeneres Show

as Self

(1987) thirtysomething

as ---

(1952) Today

as Self

(1988) LIVE with Kelly and Mark

as ---

(1989) Tales from the Crypt

as Mary Jo

(1997) The View

as Self

(2023) High Desert

as Peggy Newman

(1992) The Tonight Show with Jay Leno

as Self

(2001) Richard & Judy

as Self

(2012) Finding Your Roots

as Self

(1993) Late Night with Conan O'Brien

as Self - Guest

(2003) Celebrities Uncensored

as Self

(2005) The Late Late Show with Craig Ferguson

as Self

(2017) Carpool Karaoke: The Series

as Self

(2001) Good Day Live

as Self

(2000) CSI: Crime Scene Investigation

as Avery Ryan

(2015) The Late Late Show with James Corden

as Self

(2015) CSI: Cyber

as Avery Ryan

(1999) Law & Order: Special Victims Unit

as Jeannie Kerns

(1993) Intimate Portrait

as Self

(2018) The Issue Is

as Self

(2018) Escape at Dannemora

as Joyce "Tilly" Mitchell

(2014) The Tonight Show Starring Jimmy Fallon

as Self

(2014) Variety Studio: Actors on Actors

as Self

(2009) Watch What Happens Live with Andy Cohen

as Self - Guest

(2019) The Act

as Dee Dee Blanchard

(2022) Severance

as Harmony Cobel

(2015) Close Up with The Hollywood Reporter

as Self

(1990) The Outsiders

as Rhonda Sue

Untitled Murdaugh Murders Series

as Maggie

(2006) The Megan Mullally Show

as Self - Guest