Nicolas Cage

Frank Pierce

Patricia Arquette

Mary Burke

John Goodman

Larry Verber

Ving Rhames

Marcus

Tom Sizemore

Tom Wolls

Marc Anthony

Noel

Mary Beth Hurt

Nurse Constance

Cliff Curtis

Cy Coates

Aida Turturro

Nurse Crupp

Nestor Serrano

Dr. Hazmat

Cynthia Roman

Rose

Sonja Sohn

Kanita

Larry Fessenden

Cokehead

Arthur J. Nascarella

Captain Barney

Martin Scorsese

Dispatcher (voice)

Queen Latifah

Dispatcher Love (voice)

Michael Kenneth Williams

Drug Dealer

Craig muMs Grant

Voice in Crowd

John Heffernan

Mr. Oh

Judy Reyes

ICU Nurse

Afemo Omilami

Griss

Cullen O. Johnson

Mr. Burke

Julyana Soelistyo

Sister Fetus

Graciela Lecube

Neighbor Woman

Marylouise Burke

Neighbor Woman

Phyllis Somerville

Mrs. Burke

Mary Diveny

Neighbor Woman

Tom Riis Farrell

John Burke

Aleks Shaklin

Arguing Russian

Leonid Citer

Arguing Russian

Jesus A. Del Rosario Jr.

Man with Bloody Foot

Bernie Friedman

Big Feet

Theo Kogan

Prostitute

Fuschia!

Prostitute

Matthew Maher

Mr. Oh's Friend

Bronson Dudley

Mr. Oh's Friend

Marilyn McDonald

Mr. Oh's Friend

Ed Jupp Jr.

Homeless Man in Waiting Room

J. Stanford Hoffman

Homeless Man in Waiting Room

Rita Norona Schrager

Concerned Hispanic Aunt

Don Berry

Naked Man

Mtume Gant

Street Punk

Michael A. Noto

Grunt

Omar Scroggins

Bystander

Andy Davoli

Stanley

Charlene Hunter

Miss Williams

Jesse Malin

Club Doorman

Harper Simon

I.B. Bangin'

Joseph Monroe Webb

Drummer

Jon Abrahams

Club Bystander

Charis Michelsen

I.B.'s Girlfriend

Lia Yang

Dr. Milagros

Antone Pagán

Arrested Man

Melissa Marsala

Bridge & Tunnel Girl

Betty Miller

Weeping Woman

Rosemary Gomez

Pregnant Maria

Luis Rodriguez

Carlos

Sylva Kelegian

Crackhead

Frank Ciornei

Dr. Mishra

Catrina Ganey

Nurse Odette

Jennifer Lane Newman

Nurse Advisor

John Bal

Police in Hospital

Raymond Cassar

Police in Hospital

Tom Cappadona

Drunk

Jack O'Connell

Drunk

Randy Foster

Drunk

Richard Spore

Homeless Suicidal

James Hanlon

Fireman

Chris Edwards

Fireman

Mark Giordano

Police Sergeant

Michael Mulheren

Cop in Elevator

David Zayas

Cop in Elevator

Terry Serpico

Cop #1

Floyd Resnick

Cop #3

Megan Leigh

Surgeon

David Vasquez

Screaming Man

Joseph P. Reidy

ICU Doctor

Erica Bamforth

Urchin Prostitute (uncredited)

Peju Bamgboshe

Child Zombie (uncredited)

Carolyn Campbell

Policewoman (uncredited)

Michael Carbonaro

Club Kid (uncredited)

Joe Connelly

Catatonic Patient in Suede Coat (uncredited)

Brian Smyj

Cop #2 (uncredited)