Robert De Niro

Leonard Lowe

Robin Williams

Malcolm Sayer

John Heard

Dr. Kaufman

Julie Kavner

Eleanor Costello

Penelope Ann Miller

Paula

Ruth Nelson

Mrs. Lowe

Max von Sydow

Peter Ingham

Anne Meara

Miriam

Dexter Gordon

Rolando

George Martin

Frank

Alice Drummond

Lucy Fishman

Richard Libertini

Sidney

Laura Esterman

Lolly

Barton Heyman

Bert

Judith Malina

Rose

Mary Alice

Nurse Margaret

Keith Diamond

Anthony

Bradley Whitford

Dr. Tyler

John Christopher Jones

Dr. Sullivan

Mary Catherine Wright

Nurse Beth

Jayne Haynes

Frances

Le Clanché du Rand

Magda

Yusef Bulos

Joseph

Steven Randazzo

Luis

Gloria Harper

Dottie

Gwyllum Evans

Desmond

Steve Vinovich

Ray

Tiger Haynes

Janitor

Harvey Miller

Hospital Director

Tanya Berezin

Psychiatrist

Peter Stormare

Neurochemist

Shane Fistell

Man in Hall

Waheedah Ahmad

Hysterical Woman

Charles Keating

Mr. Kean

Christina Huertes

Christina

Linda Burns

Fishsticks

Judy Jacksina

Hospital Receptionist

Gary Tacon

George

Rico Elias

Orderly #1

Mel Gorham

Nurse Sara

Chris Carolan

EEG Technician

Debra Kovner-Zaks

Cafeteria Nurse

Bret McCormick

Head Ward Orderly

Gordon Joseph Weiss

Ward #5 Patient

Byron Utley

Ward #5 Patient #2

Anthony McGowen

Ward #5 Patient #3

Paul Montgomery

Ward #5 Patient #4

Leonard Tepper

Ward #5 Patient #5

Vincent Pastore

Ward #5 Patient #6

Howard Feller

Ward #5 Patient #7

Libby Titus

Club Singer

Michael Hyde

Bus Driver

Tomislav Novakovic

Bartender

Adam Bryant

Librarian

Anthony J. Nici

Young Leonard

Oliver Block

Leonard's Friend #1

Buck Smith

Leonard's Friend #2

Joan E. MacIntosh

Teacher

Harry L. Seddon

Medical Student

Jack Mulcahy

Psych Ward Intern

Jason W. Fuchs

Pot-Head Hippie

Vin Diesel

Hospital Orderly (uncredited)