September 2, 2008
Episode 1 of Season 16 premiered on September 2, 2008
September 3, 2008
Episode 2 of Season 16 premiered on September 3, 2008
September 4, 2008
Episode 3 of Season 16 premiered on September 4, 2008
September 5, 2008
Episode 4 of Season 16 premiered on September 5, 2008
September 8, 2008
Episode 5 of Season 16 premiered on September 8, 2008
September 9, 2008
Episode 6 of Season 16 premiered on September 9, 2008
September 10, 2008
Episode 7 of Season 16 premiered on September 10, 2008
September 11, 2008
Episode 8 of Season 16 premiered on September 11, 2008
September 12, 2008
Tonight's guests include Eva Mendes and Luke Russert. The Fab Faux perform.
September 15, 2008
Episode 10 of Season 16 premiered on September 15, 2008
September 16, 2008
Tonight's guests include Martha Stewart and Harland Williams. Kasey Chambers & Shane Nicholson perform.
September 17, 2008
Episode 12 of Season 16 premiered on September 17, 2008
September 18, 2008
Tonight's guests include Anderson Cooper and Willie Nelson. Southside Johnny with La Bamba's Big Band perform.
September 19, 2008
Episode 14 of Season 16 premiered on September 19, 2008
September 22, 2008
Tonight's guests include Diane Lane and Patton Oswalt. Little Feat perform.
September 23, 2008
Episode 16 of Season 16 premiered on September 23, 2008
September 24, 2008
Tonight's guests include Jamie Pressly and Little Britain. Lenka Kripac performs.
September 25, 2008
Tonight's guests include Julianne Moore and Zachary Levi. Jakob Dylan performs.
September 26, 2008
Tonight's guests include Brooke Shields and Robert Reich. Amos Lee performs.
September 29, 2008
Tonight's guests include Bill Maher and Simon Pegg. The Watson Twins perform.
September 30, 2008
Episode 21 of Season 16 premiered on September 30, 2008
October 1, 2008
Episode 22 of Season 16 premiered on October 1, 2008
October 2, 2008
Tonight's guests include Tom Arnold and Flavor Flav. Ben Folds performs "You Don't Know Me" with Regina Spektor.
October 3, 2008
Episode 24 of Season 16 premiered on October 3, 2008
October 6, 2008
Episode 25 of Season 16 premiered on October 6, 2008
October 7, 2008
Episode 26 of Season 16 premiered on October 7, 2008
October 8, 2008
Episode 27 of Season 16 premiered on October 8, 2008
October 9, 2008
Tonight's guests include Dennis Quaid and Lance Mackey. Sarah McLachlan performs.
October 10, 2008
Tonight's guests include LL Cool J and Oliver Stone. Dead Confederates perform.
October 13, 2008
Tonight's guests include Christian Slater and Brian Posehn. Flobots perform.
October 14, 2008
Tonight's guests include Harry Connick Jr. and Richard Lewis. O.A.R. perform.
October 15, 2008
Tonight's guests include Bill Murray and Rob Corddry. Ray LaMontagne performs.
October 16, 2008
Tonight's guests include Josh Brolin and Shaun Ellis & Helen Jeffs. Nikka Costa performs.
October 17, 2008
Tonight's guests include Edward Norton and Chris "Ludacris" Bridges. Mike Birbiglia performs.
October 27, 2008
Tonight's guests include Charles Barkley and Justin Long. The Annuals perform.
October 28, 2008
Tonight's guests include Tina Fey and Peter Sarsgaard. The Black Crowes perform.
October 29, 2008
Tonight's guests include Tracy Morgan and Paget Brewster. The Last Shadow Puppets perform.
October 30, 2008
Tonight's guests include Jada Pinkett-Smith and Jason Biggs. Pink performs.
October 31, 2008
Tonight's guests include Mary-Kate Olsen, Will Forte and Tom Nardone.
November 3, 2008
Tonight's guests include Brian Williams and Bill Bellamy. The Decemberists perform.
November 5, 2008
Tonight's guests include Dennis Hopper and Katt Williams. Phil Lesh & Friends perform.
November 6, 2008
Tonight's guests include Elvis Costello and Madeleine Albright. Lordi perform.
November 7, 2008
Episode 43 of Season 16 premiered on November 7, 2008
November 10, 2008
Episode 44 of Season 16 premiered on November 10, 2008
November 11, 2008
Tonight's guests include Seth Green and Artie Lange. Conor Oberst & The Mystic Valley Band perform.
November 12, 2008
Tonight's guests include Tom Brokaw and Frank Caliendo. Joshua Radin performs.
November 13, 2008
Tonight's guests include Paul Rudd and John Stamos. Boz Scaggs performs.
November 14, 2008
Episode 48 of Season 16 premiered on November 14, 2008
November 17, 2008
Tonight's guests include Snoop Dogg and Brian Regan. Blitzen Trapper perform.
November 18, 2008
Episode 50 of Season 16 premiered on November 18, 2008
November 19, 2008
Episode 51 of Season 16 premiered on November 19, 2008
November 20, 2008
Episode 52 of Season 16 premiered on November 20, 2008
November 21, 2008
Episode 53 of Season 16 premiered on November 21, 2008
November 24, 2008
Episode 54 of Season 16 premiered on November 24, 2008
November 25, 2008
Episode 55 of Season 16 premiered on November 25, 2008
November 26, 2008
Episode 56 of Season 16 premiered on November 26, 2008
December 8, 2008
Episode 57 of Season 16 premiered on December 8, 2008
December 9, 2008
Episode 58 of Season 16 premiered on December 9, 2008
December 10, 2008
Episode 59 of Season 16 premiered on December 10, 2008
December 11, 2008
Episode 60 of Season 16 premiered on December 11, 2008
December 12, 2008
Don Rickles, John Leguizamo, and musical guest Erran Baron Cohen
December 15, 2008
Episode 62 of Season 16 premiered on December 15, 2008
December 16, 2008
Tonight's guests include Eva Mendes and Ken Mink. The Fleet Foxes perform.
December 17, 2008
Episode 64 of Season 16 premiered on December 17, 2008
December 18, 2008
Tonight's guests include Matthew Broderick and Paul F. Tompkins. Little Big Town perform.
December 19, 2008
Tonight's guests include Jennifer Aniston and Judah Friedlander. Pilobolus perform.
December 22, 2008
Tonight's guests include Carson Daly and Steve Schirripa. Bela Fleck and the Flecktones perform.
December 23, 2008
Tonight's guests include Dustin Hoffman and Greg Giraldo. Greg Giraldo and the Old Crow Medicine Show perform.
January 5, 2009
Episode 69 of Season 16 premiered on January 5, 2009
January 6, 2009
Episode 70 of Season 16 premiered on January 6, 2009
January 7, 2009
Episode 71 of Season 16 premiered on January 7, 2009
January 8, 2009
Episode 72 of Season 16 premiered on January 8, 2009
January 12, 2009
Episode 73 of Season 16 premiered on January 12, 2009
January 13, 2009
Episode 74 of Season 16 premiered on January 13, 2009
January 14, 2009
Episode 75 of Season 16 premiered on January 14, 2009
January 15, 2009
Bob Costas, Fred Armisen, Robert Schimmel
January 19, 2009
Teri Hatcher, Aries Spears, Q-Tip
January 20, 2009
Episode 78 of Season 16 premiered on January 20, 2009
January 21, 2009
Episode 79 of Season 16 premiered on January 21, 2009
January 22, 2009
Episode 80 of Season 16 premiered on January 22, 2009
January 26, 2009
Episode 81 of Season 16 premiered on January 26, 2009
January 27, 2009
Episode 82 of Season 16 premiered on January 27, 2009
January 28, 2009
Episode 83 of Season 16 premiered on January 28, 2009
January 29, 2009
Episode 84 of Season 16 premiered on January 29, 2009
February 2, 2009
Episode 85 of Season 16 premiered on February 2, 2009
February 3, 2009
Episode 86 of Season 16 premiered on February 3, 2009
February 4, 2009
Episode 87 of Season 16 premiered on February 4, 2009
February 5, 2009
Episode 88 of Season 16 premiered on February 5, 2009
February 9, 2009
Tonight Conan welcomes Clive Owen, Judah Friedlander and musical guest Brett Dennen.
February 10, 2009
Tonight Conan welcomes Norm MacDonald, Gordon Ramsay and musical guest Levon Helm.
February 11, 2009
Tonight Conan welcomes Jimmy Fallon, Rose Byrne and musical guest John Pizzarelli.
February 12, 2009
Tonight Conan welcomes Alec Baldwin, Eliza Dushku and musical guest They Might Be Giants.
February 13, 2009
Tonight Conan welcomes Isla Fisher, The Jonas Brothers and musical guest Dan Auerbach.
February 16, 2009
Tonight Conan welcomes Bob Saget and musical guest Thenewno2.
February 17, 2009
Tonight Conan welcomes Jason Sudeikis.
February 18, 2009
Tonight Conan welcomes Nathan Lane and Martha Stewart.
February 19, 2009
Tonight Conan welcomes Jerry Seinfeld and Craig Bierko.
February 20, 2009
Tonight Conan welcomes musical guest The White Stripes.