(1990) Edward Scissorhands

as Kim

(1991) Night on Earth

as Corky

(1993) The House of the Spirits

as Blanca Trueba

(2022) Gone in the Night

as Kath

(2006) A Scanner Darkly

as Donna Hawthorne

(2000) Autumn in New York

as Charlotte Fielding

(1999) Girl, Interrupted

as Susanna

(1988) Heathers

as Veronica Sawyer

(2002) Mr. Deeds

as Babe Bennett

(2000) Lost Souls

as Maya Larkin

(1988) Beetlejuice

as Lydia

(1994) Reality Bites

as Lelaina Pierce

(1993) The Age of Innocence

as May Welland

(1990) Mermaids

as Charlotte Flax

(2009) The Private Lives of Pippa Lee

as Sandra Dulles

(1996) The Crucible

as Abigail Williams

(2009) Stay Cool

as Scarlet Smith

(1989) Great Balls of Fire!

as Myra Gale Brown

(1997) Alien Resurrection

as Call

(1990) Welcome Home, Roxy Carmichael

as Dinky Bossetti

(1995) How to Make an American Quilt

as Finn Dodd

(1998) Celebrity

as Nola

(2002) S1m0ne

as Nicola Anders

(1994) Little Women

as Jo March

(2001) Zoolander

as Winona Ryder (uncredited)

(1986) Lucas

as Rina

(2007) The Ten

as Kelly La Fonda

(2009) Star Trek

as Amanda Grayson

(2007) Sex and Death 101

as Death Nell / Gillian De Raisx (#101)

(1996) Looking for Richard

as Self / Lady Anne

(1996) Boys

as Patty Vare

(2011) The Dilemma

as Geneva Brannen

(2012) Frankenweenie

as Elsa Van Helsing (voice)

(2010) Black Swan

as Beth Macintyre / The Dying Swan

(2008) The Informers

as Cheryl Moore

(2008) The Last Word

as Charlotte Morris

(2006) The Darwin Awards

as Siri Taylor

(1988) 1969

as Beth Carr

(2012) The Iceman

as Deborah Kuklinski

(2010) When Love Is Not Enough: The Lois Wilson Story

as Lois Wilson

(2024) Beetlejuice Beetlejuice

as Lydia

(2003) One Step Beyond: The Making of Alien Resurrection

as Self

(2022) The Mojo Manifesto: The Life and Times of Mojo Nixon

as Self

(2007) Marc Jacobs & Louis Vuitton

as Herself

(1987) Square Dance

as Gemma

(2012) The Letter

as Martine Jamison

(2022) Winona Ryder: The Ghosts She Called

as Self - Actress (archive footage)

(2007) Welcome

as Cynthia

(2013) Homefront

as Sheryl Marie Mott

(2021) Hannibal Hopkins & Sir Anthony

as Self (archive footage)

(2014) Turks & Caicos

as Melanie Fall

(2004) The Heart Is Deceitful Above All Things

as Psychologist

(2004) Cabin Fever: Beneath the Skin

as (archive footage) (uncredited)

(2001) Swatch Dogs and Diet Coke Heads

as Self

(2023) Haunted Mansion

as Pat (uncredited)

(2012) Ben Lee: Catch My Disease

as Self

(2015) Experimenter

as Alexandra "Sasha" Milgram

(2005) Nos Bastidores de Hollywood

as Self

(1992) Blood Lines: Dracula - The Man. The Myth. The Movies.

as Self

(2003) Declaration of Independence

as Self

(2016) Author: The JT LeRoy Story

as Herself

(2018) Destination Wedding

as Lindsay

(1993) Innocence and Experience: The Making of 'The Age of Innocence'

as Self

(2011) Black Swan: Metamorphosis

as Self

(2007) Voom Portraits

as Self

(2003) The Day My God Died

as Narrator (voice)

(2006) One Summer in Austin: The Story of Filming 'A Scanner Darkly'

as Self / Donna

(1990) The Making of Edward Scissorhands

as Self

(1992) Bram Stoker's Dracula

as Mina Murray / Elisabeta

(2020) Sarah Cooper: Everything's Fine

as Lacey Groin

(2007) The Blood Is the Life: The Making of 'Bram Stoker's Dracula'

as Self (archive footage)

(1989) The Simpsons

as Allison Taylor (voice)

(1994) Friends

as Melissa Warburton

(1999) Strangers with Candy

as Fran

(1992) The Larry Sanders Show

as Winona Ryder

(1995) Dr. Katz, Professional Therapist

as ---

(2003) Celebrities Uncensored

as Self

(1953) The Oscars

as Self

(2015) Show Me a Hero

as Vinni Restiano

(1975) Saturday Night Live

as Self - Host

(2014) Late Night with Seth Meyers

as Self

(2016) Stranger Things

as Joyce Byers

(1996) E! True Hollywood Story

as Self

(2020) The Plot Against America

as Evelyn Finkel

(1975) Saturday Night Live

as Self - Cameo (uncredited)

(2013) Drunk History

as Mary Dyer