(2006) The Holiday

as Bristol

(2007) The Last Mimzy

as Naomi Schwartz

(2004) Anchorman: The Legend of Ron Burgundy

as Helen

(2008) Step Brothers

as Alice

(2005) A Lot Like Love

as Michelle

(2004) Wake Up, Ron Burgundy: The Lost Movie

as Helen

(2003) How to Lose a Guy in 10 Days

as Michelle Rubin

(2004) Win a Date with Tad Hamilton!

as Angelica

(2021) Marvel Studios' 2021 Disney+ Day Special

as Agnes / Agatha Harkness (archive footage)

(2021) Live in Front of a Studio Audience: The Facts of Life and Diff'rent Strokes

as Jo Polniaczek

(2010) How Do You Know

as Annie

(2004) Around the Bend

as Sarah

(2012) Wanderlust

as Karen

(2009) The Goods: Live Hard, Sell Hard

as Babs Merrick

(2023) Spider-Man: Across the Spider-Verse

as Doc Ock (voice)

(2012) The Dictator

as Pregnant Woman

Fixed

as Honey (voice)

(2011) Our Idiot Brother

as Janet

(2013) The Secret Life of Walter Mitty

as Odessa Mitty

(2013) Afternoon Delight

as Rachel

(2013) We're the Millers

as Edie Fitzgerald

(2013) Bad Words

as Jenny Widgeon

(2014) This Is Where I Leave You

as Annie Altman

(2015) She's Funny That Way

as Delta Simmons

(2008) Revolutionary Road

as Milly Campbell

(2015) The Visit

as Loretta Jamison

(2015) The D Train

as Stacey Landsman

(2015) Tomorrowland

as Ursula

(2016) Captain Fantastic

as Harper

(2015) Len and Company

as Isabelle

(2013) Timms Valley

as Daniel Myers

(1999) Flushed

as ---

(2013) Dark Around the Stars

as Judith

(2016) The Do-Over

as Becca

(2016) Bad Moms

as Carla Dunkler

(2016) The Family Fang

as Young Camille

(2017) Flower

as Laurie

(2017) A Bad Moms Christmas

as Carla Dunkler

(2018) Private Life

as Rachel Biegler

(2018) Hotel Transylvania 3: Summer Vacation

as Ericka Van Helsing (voice)

(2018) Spider-Man: Into the Spider-Verse

as Doc Ock (voice)

(2019) Transparent: Musicale Finale

as Raquel Fein

(2022) Hotel Transylvania: Transformania

as Ericka Van Helsing (voice)

(2019) Marvel Studios: Expanding the Universe

as Self

(2022) Glass Onion: A Knives Out Mystery

as Claire Debella

The Sisters Rosensweig

as Gorgeous

(2011) Razzle Dazzle

as Paula Gross

(2011) Razzle Dazzle Part 2

as Paula Gross

(2024) E. Jean Carroll V. Donald J. Trump

as E. Jean Carroll

(2024) Marvel Studios Assembled: The Making of Agatha All Along

as Self - Agatha Harkness

(2006) Four Kings

as Sharon

(2001) Crossing Jordan

as Lily Lebowski

(1997) The View

as Self - Guest

(2012) The Greatest Event in Television History

as Sara Rush

(2012) The Greatest Event in Television History

as Greta Strauss

(2021) Marvel Studios Assembled

as Self - Agnes

(2014) The Tonight Show Starring Jimmy Fallon

as Self

(2014) Transparent

as Raquel Fein

(2014) Chozen

as Tracy

(2019) A Little Late with Lilly Singh

as Self

(2005) The Late Late Show with Craig Ferguson

as Self

(2011) Free Agents

as Helen Ryan

(2009) Parks and Recreation

as Jennifer Barkley

(2012) Girls

as Katherine Lavoyt

(2015) HAPPYish

as Lee Payne

(2021) Marvel Studios Legends

as Agnes / Agatha Harkness (archive footage) (uncredited)

(2016) Angie Tribeca

as Susan

(2012) Comedy Bang! Bang!

as Self

(2014) Late Night with Seth Meyers

as Self

(2024) Agatha All Along

as Agnes O'Connor / Agatha Harkness

(2015) The Late Late Show with James Corden

as Self

(2016) I Love Dick

as Chris

(2009) Hung

as Claire

(2014) Celebrity Name Game

as Self

(2011) Bob's Burgers

as Jessica (voice)

(2020) The Drew Barrymore Show

as Self

(2023) Tiny Beautiful Things

as Clare Pierce

(2019) Mrs. Fletcher

as Eve Fletcher

(2020) I Know This Much Is True

as Dessa Constantine

(2025) The Studio

as Maya

(2021) Ultra City Smiths

as Daniel Myers

(2013) Brooklyn Nine-Nine

as Eleanor

(1981) Entertainment Tonight

as Self

(2021) WandaVision

as Agnes / Agatha Harkness

(2008) Childrens Hospital

as Lamaze Teacher

(2013) Kroll Show

as Mikey's Mom

(2005) Robot Chicken

as Mrs. Marquez, T-Shirt Girl #1 (voice)

(2014) Last Week Tonight with John Oliver

as Wife

(2011) Mad Love

as Chef Linda Clay

(2011) NTSF:SD:SUV::

as Marge

(2012) The Newsroom

as Carrie

(2011) Traffic Light

as Kate

(2009) Watch What Happens Live with Andy Cohen

as Self - Guest

(2005) American Dad!

as Luli (voice)

(2020) Central Park

as Paige (voice)

(2015) Close Up with The Hollywood Reporter

as Self

(2018) The Romanoffs

as Anka

(2014) Off Camera with Sam Jones

as Self

(2003) Jimmy Kimmel Live!

as Self - Guest Host

(1981) Hickory Hideout

as Jenny

(2020) Die Hart

as Jillian Avery

(2021) The Shrink Next Door

as Phyllis Shapiro

(2014) Variety Studio: Actors on Actors

as Self

(2021) What If...?

as Agatha Harkness (voice)