Peter Weller

Bruce Wayne / Batman (voice)

Ariel Winter

Carrie Kelley / Robin (voice)

David Selby

Commissioner James Gordon (voice)

Wade Williams

Harvey Dent / Two-Face (voice)

Michael Emerson

Joker (voice)

Dee Bradley Baker

Don / Fat Mutant / Additional Voices (voice)

Maria Canals-Barrera

Commissioner Ellen Yindel (voice)

Paget Brewster

Lana Lang (voice)

Richard Doyle

The Mayor (voice)

Michael Jackson

Alfred Pennyworth (voice)

Yuri Lowenthal

The Son of Batman / Rookie Police Officer (voice)

Michael McKean

Dr. Bartholomew Wolper (voice)

James Patrick Stuart

Murray / Radio Voice (voice)

James Arnold Taylor

Mr. Hudson / Spud (voice)

Bruce Timm

Thomas Wayne / Hydrant Fireman (voice)

Frank Welker

Mayor Stevenson / Weather Man (voice)

Gary Anthony Williams

Mutant Leader / Anchor Bill (voice)

Rob Paulsen

Jeff Adams (voice)

Mark Valley

Clark Kent / Superman (voice)

Robin Atkin Downes

Oliver Queen (voice)

Tress MacNeille

Selina Kyle / Bruno / Old Woman(voice)

Jim Meskimen

President Ronald Reagan (voice)

Conan O'Brien

David Endochrine (voice)

Andy Richter

Frank (voice, uncredited)

Grey DeLisle

Anchor Carla / Female Mutant (voice)

Gary Anthony Sturgis

Silk / Other Spike / Young Mutant (voice)

Carlos Alazraqui

Hernando / TV Host (voice)

Cathy Cavadini

Joanie / Woman with Hot Dog (voice)

Greg Eagles

Mackie / Ben Derrick (voice)

Townsend Coleman

Morrie / Civilian (voice)

Maurice LaMarche

Dr. Willing / News Anchor (voice)

Sam McMurray

Anchor Ted (voice)

Tara Charendoff-Strong

Young Bruce Wayne / Additional Voices (voice)

Andrea Romano

Woman / Police Dispatch / Woman #2 (voice)

Gwendoline Yeo

Lola Chong (voice)

Manny Jacobs

Merkel (voice)

Jim Wise

Femur (voice)

Lex Lang

Rescued Man (voice)

Jason Charles Miller

Axe Fireman (voice)