Tom Cruise

Frank T.J. Mackey

Philip Baker Hall

Jimmy Gator

Philip Seymour Hoffman

Phil Parma

Julianne Moore

Linda Partridge

William H. Macy

Quiz Kid Donnie Smith

John C. Reilly

Officer Jim Kurring

Melora Walters

Claudia Wilson Gator

Jeremy Blackman

Stanley Spector

Jason Robards

Earl Partridge

Melinda Dillon

Rose Gator

Michael Bowen

Rick Spector

April Grace

Gwenovier

Ricky Jay

Burt Ramsey / Narrator

Emmanuel Johnson

Dixon

Pat Healy

Sir Edmund William Godfrey / Young Pharmacy Kid

Genevieve Zweig

Mrs. Godfrey

Mark Flanagan

Joseph Green

Neil Flynn

Stanley Berry

Rod McLachlan

Daniel Hill

Allan Graf

Firefighter

Patton Oswalt

Delmer Darion

Raymond 'Big Guy' Gonzales

Reno Security Guard

Brad Hunt

Craig Hansen

Jim Meskimen

Forensic Scientist

Chris O'Hara

Sydney Barringer

Clement Blake

Arthur Barringer

Frank Elmore

1958 Detective

John Kraft Seitz

1958 Policeman

Cory Buck

Young Boy

Tim Soronen

Infomercial Guy

Jim Ortlieb

Middle-Aged Guy

Thomas Jane

Young Jimmy Gator

Holly Houston

Jimmy's Showgirl

Benjamin Niedens

Little Donnie Smith

Veronica Hart

Dentist Nurse #1

Missy Spell Tanner

Dentist Nurse #2

James Kiriyama-Lem

Dr. Lee

Jake Cross

Pedestrian #1

Charlie Scott Jr.

Pedestrian #2

Juan Medrano

Nurse Juan

John Pritchett

Police Captain

Cleo King

Marcie

Don McManus

Dr. Landon

Michael Shamus Wiles

Captain Muffy

Jason Andrews

Doc

John S. Davies

Cameraman

Kevin Breznahan

Geoff, Seminar Guy

Miguel Pérez

Avi Solomon

Alfred Molina

Solomon Solomon

David Masuda

Coroner Man

Neil Pepe

Officer #1

Lionel Mark Smith

Detective

Annette Helde

Coroner Woman

Lynne Lerner

Librarian

Felicity Huffman

Cynthia

Scott Burkett

WDKK Page #1

Bob Brewer

Richard's Dad

Julie Brewer

Richard's Mom

Nancy Marston

Julia's Mom

Maurey Marston

Julia's Dad

Jamala Gaither

WDKK P.A.

Danny Wells

Dick Jennings

Amy Brown

WDKK Page #2

Eileen Ryan

Mary

Meagen Fay

Dr. Diane

Patricia Forte

Mim

Luis Guzmán

Luis

Patrick Warren

Todd Geronimo

Orlando Jones

Worm

Virginia Pereira

Pink Dot Girl (voice)

Craig Kvinsland

Brad the Bartender

Patricia Scanlon

Cocktail Waitress

Henry Gibson

Thurston Howell

Natalie Elizabeth Marston

Julia

Bobby Brewer

Richard

Clark Gregg

WDKK Floor Director

Art Frankel

Old Pharmacist

Matt Gerald

Officer #2

Guillermo Melgarejo

Pink Dot Guy

Paul F. Tompkins

Chad (Seduce & Destroy) (voice)

Mary Lynn Rajskub

Janet (Frank's Assistant) (voice)

Jim Beaver

Smiling Peanut Patron #1

Ezra Buzzington

Smiling Peanut Patron #2

Denise Woolfork

Smiling Peanut Patron #3

Michael Murphy

Alan Kligman, Esq.

Robert Downey Sr.

WDKK Show Director

William Mapother

WDKK Show Director's Assistant

Larry Ballard

WDKK Medic

Brett Higgins

Mackey Disciple Twin #1

Brian Higgins

Mackey Disciple Twin #2

Michael Lee Phillips Jr.

Mackey Disciple in Middle

Lillian Adams

Donnie's Old Neighbor

Steven Bush

Paramedic #1

Mike Massa

Paramedic #2

Dale Gibson

Paramedic #3

Scott Alan Smith

E.R. Doctor

Paul Thomas Anderson

Man Confiscating Sign (uncredited)

Miriam Margolyes

Faye Barringer (uncredited)

Bruno Angelico

Fireman #2 (uncredited)

Robert Bella

Detective #2 (uncredited)

Greg Bronson

Waiter (uncredited)

Douglas Busby

Extra (uncredited)

Marc Davies

Seminar Attendee #1 (uncredited)

Bruce Gregory

Randy (uncredited)

Phil Hawn

Bob (uncredited)

Spencer Kayden

Seminar Patron (uncredited)

Brian Kehew

Seminar Patron (uncredited)

Michael Laren

Officer Tom 1958 (uncredited)

Aimee Mann

Hot Date Infomercial (uncredited)

Tom Ohmer

Detective (uncredited)

Colleen Pelletier

Gameshow Audience Member (uncredited)

Herb Santos Jr.

21 Dealer (uncredited)

Tom Tangen

Drunken Dart Player (uncredited)