John Wayne

Thomas Dunson

Montgomery Clift

Matthew Garth

Joanne Dru

Tess Millay

Walter Brennan

'Groot' Nadine

Coleen Gray

Fen

Harry Carey

Mr. Melville

John Ireland

Cherry Valance

Noah Beery Jr.

Buster McGee

Harry Carey, Jr.

Dan Latimer

Chief Yowlachie

Quo

Paul Fix

Teeler Yacey

Hank Worden

Simms Reeves

Mickey Kuhn

Matt, as a boy

Ray Hyke

Walt Jergens

Hal Taliaferro

Old Leather

Shelley Winters

Dance Hall Girl in Wagon Train (uncredited)

Lane Chandler

Colonel (uncredited)

Davison Clark

Mr. Meeker (uncredited)

Harry Cording

Gambler (uncredited)

Richard Farnsworth

Dunston Rider (uncredited)

Paul Fierro

Fernandez (uncredited)

George Lloyd

Rider with Melville (uncredited)

Pierce Lyden

Colonel's Trail Boss (uncredited)

Frank Meredith

Train Engineer (uncredited)

John Merton

Settler (uncredited) (uncredited)

Jack Montgomery

Drover at Meeting (uncredited)

Ivan Parry

Bunk Kenneally (uncredited)

Lee Phelps

Gambler (uncredited)

John Rice

Drover at Meeting (uncredited)

William Self

Sutter (uncredited)

Carl Sepulveda

Cowhand (uncredited)

Ray Spiker

Wagon Train Member (uncredited)

Glenn Strange

Naylor (uncredited)

Tom Tyler

Quitter (uncredited)

Dan White

Laredo (uncredited)

Guy Wilkerson

Pete (uncredited)

Shelley Winters

Wagon Train Member (uncredited)