Rob Lowe

John F. Kennedy

Will Rothhaar

Lee Harvey Oswald

Ginnifer Goodwin

Jacqueline Kennedy

Michelle Trachtenberg

Marina Oswald

Jack Noseworthy

Robert F. Kennedy

Casey Siemaszko

Jack Ruby

Jamie McShane

Richard Snyder

Mary Pat Gleason

Marguerite Oswald

Boris McGiver

John Fain

Antoinette LaVecchia

Lady Bird Johnson

Francis Guinan

Lyndon B. Johnson

Richard Flood

Kenny O'Donnell

Jody Matzer

Lead Trauma Surgeon

Boris McGiver

FBI Agent

Brian Hutchison

Winston Lawson

Peter Rini

Agent Mooney

Roger W. Durrett

Admiral Burke

Danny McCarthy

Agent James Hosty

Parker Dowling

Buell Wesley Frazier

Mike Shiflett

Captain Will Fritz

Natalie Gold

Ruth Paine

Juan Pablo Veizaga

Carlos Bringuier

Jason B. McIntosh

Charles Givens

Richard Warner

Chester Bowles

William L. Thomas

Clint Hill

Angelo Reyes

First Cuban

Jose Luis Munoz

Second Cuban

Terry Menefee Gau

Nurse Doris Nelson

Bonnie Johnson

Earlene Roberts

Joe Duquette

Eusebio Azcue

John Moon

Father Oscar Huber

Demosthenes Chrysan

George De Mohrenschildt

Solomon Gibson III

George Thomas

Keith Tyree

Governor John Connolly

Ford Flannagan

Howard Brennan

Pete Burris

John Quigley

Ray Nedzel

McGeorge Bundy

Charles Wissinger

Malcolm Kilduff

L. Derek Leonidoff

Marion Baker

Matt Micou

Officer J.D. Tippit

Dan Stearns

Reporter

Gregory Williams

Roy Truly

Robert C. Treveiler

Sheriff's Deputy

Mark Ziv

Sterling Wood

Jonathan Orcutt

William Whaley

Christopher Wiehl

Agent O'Reilly

Mitchell Hebert

Forrest Sorrels

Peter Toney

Officer Harry Hunter

Jefferson Farber

Worker

Bart Debicki

Max

Mike Marunde

Mike

Shaun Irving

Officer

Taylor Roberts

Faddle

Joseph Gray

Sergeant Gerald Hill

Bo Keister

Tony - Bartender

Chris Van Cleave

Doctor George Burkley

Adrienne Nelson

Nell Connally

Kirsten Hauser

Fiddle

Lucas N. Hall

Officer Atwell, Dallas P.D.