Dan Aykroyd

Louis Winthorpe III

Eddie Murphy

Billy Ray Valentine

Ralph Bellamy

Randolph Duke

Don Ameche

Mortimer Duke

Denholm Elliott

Coleman

Kristin Holby

Penelope Witherspoon

Paul Gleason

Clarence Beeks

Jamie Lee Curtis

Ophelia

Alfred Drake

President of Exchange

Bo Diddley

Pawnbroker

Frank Oz

Corrupt Cop

Jim Belushi

Harvey

Al Franken

Baggage Handler #1

Tom Davis

Baggage Handler #2

Maurice Woods

Duke & Duke Employee

Richard D. Fisher, Jr.

Duke & Duke Employee

Jim Gallagher

Duke & Duke Employee

Anthony DiSabatino

Duke & Duke Employee

Bonnie Behrend

Duke & Duke Employee

Sunnie Merrill

Duke & Duke Employee

James Newell

Duke & Duke Employee

Mary St. John

Duke & Duke Employee

Bonnie Tremena

Duke & Duke Employee

David Schwartz

Duke & Duke Employee

Tom Degidon

Duke Domestic

William Magerman

Duke Domestic

Alan Dellay

Duke Domestic

Florence Anglin

Duke Domestic

Ray D'Amore

Duke Domestic

Bobra Suiter

Duke Domestic

Herb Peterson

Duke Domestic

Sue Dugan

Duke Domestic

Walt Gorney

Duke Domestic

B. Constance Barry

Duke Domestic

P. Jay Sidney

Heritage Club Doorman

Avon Long

Ezra

Tom Mardirosian

Officer Pantuzzi

Charles Brown

Officer Reynolds

Robert Curtis Brown

Todd

Nicholas Guest

Harry

John Bedford Lloyd

Andrew

Tony Sherer

Philip

Robert Earl Jones

Attendant

Robert E. Lee

Cop #1

Peter Hock

Cop #2

Clint Smith

Doo Rag Lenny

Ron Taylor

Big Black Guy

James D. Turner

Even Bigger Black Guy

Giancarlo Esposito

Cellmate #2

Steve Hofvendahl

Cellmate #3

James Eckhouse

Guard

Gwyllum Evans

President of Heritage Club

Eddie Jones

Cop #3

John McCurry

Cop #4

Michelle Mais

Hooker #1

Barra Khan

Hooker #2

Bill Cobbs

Bartender

Joshua Daniel

Party Goer

Jacques Sandulescu

Creepy Man

W.B. Brydon

Bank Manager

Margaret H. Flynn

Duke & Duke Receptionist

Kelly Curtis

Muffy

Tracey K. Shaffer

Constance

Susan Fallender

Bunny

Lucianne Buchanan

President's Mistress

Paul Garcia

Jr. Executive #1

Jed Gillin

Jr. Executive #2

Jimmy Raitt

Ophelia's Client

Kate Taylor

Duke's Secretary

Philip Bosco

Doctor

Bill Boggs

Newscaster

Deborah Reagan

Harvey's Girlfriend

Don McLeod

Gorilla

Stephen Stucker

Stationmaster

Richard Hunt

Wilson

Paul Austin

Trader #1

John Randolph Jones

Trader #2

Jack Davidson

Trader #3

Bernie McInerney

Trader #4

Maurice Copeland

Secretary of Agriculture

Ralph Clanton

Official #1

Bryan Clark

Official #2

Gary Klar

Longshoreman

Afemo Omilami

Longshoreman

Shelly Chee Chee Hall

Monica

Donna Palmer

Gladys

Barry Dennen

Demitri

Murray Bandel

Man at Police Station (uncredited)

Benjean

Stray Dog (uncredited)

John Black

Man Sitting on Couch at Party (uncredited)

John Landis

Man with Briefcase (uncredited)

Shirley Levine

Bag Lady (uncredited)

Charles Pendelton

Cop (uncredited)

Yvonna Russell

Girl in Park (uncredited)

Jan Saint

Man in Police Station (uncredited)

Arleen Sorkin

Woman at Party (uncredited)

Ronald Sylvers

Rolls Royce Driver (uncredited)

Marlene Willoughby

Woman Passed Out on Couch (uncredited)